Skip to main content

TL1 Training Program

RFA for 2016 TL1 program

The application form for the 2016 TL1 program, along with further information and instructions, is now available here.


ICTR’s TL1 Training Program began with the Clinical and Translational Science Award (CTSA) to UW-Madison in September 2007. The goal of the ICTR pre-doctoral TL1 program is to train future clinical and translational leaders and to expose all UW health-care professionals and engineering students to the scientific foundation of this discipline. This training program builds on strong clinical and translational training programs that already exist in the School of Medicine and Public Health, School of Nursing, School of Pharmacy, College of Engineering and School of Veterinary Medicine. Brief biographies and photographs of the current ICTR trainees are below.

Photos and biographies of current TL1 trainees can be viewed below. Information about previous TL1 trainees can be viewed here.

FAQ: TL1 program.


Current TL1 Trainees


Anna K Barker

Anna K Barker

Anna K Barker is a student in the Medical Scientist Training Program earning a PhD in Population Health Sciences with a focus on Epidemiology and a PhD Minor in Clinical Investigation. She earned her bachelor’s degree in Biology and Chemistry at Cornell University, Ithaca, NY. She is interested in the effects of nutrition on healthcare-acquired infection in the vulnerable elderly population. She is working with Nasia Safdar, MD, PhD, at the William Middleton Veteran’s Memorial Hospital.

Matthew E Brown

Matthew E Brown

Matthew E Brown studies with mentor, Dr. Burlingham, a seasoned expert in T cell biology and transplant immunology, and my thesis research will utilize his expertise to study mechanisms of tolerance of transplanted tissues. My previous research showed that monoclonal T cells specific for peptides of interest maintain their unique T cell receptor (TCR) rearrangement when reprogrammed into iPSCs1. These iPSCs, which serve as a virtually unlimited source of starting material, can then be re-differentiated back into a monoclonal pool of T cells bearing the TCR of interest. Additionally, it was recently shown that these re-differentiated T cells are “rejuvenated”; they bear elongated telomeres and have a more central memory phenotype compared to the input T cells3. We will take advantage of this system to explore therapeutic applications of regulatory T (Treg) cells, which play an important immunomodulatory role in tissue transplantation and in a variety of pathologies.

My research aims include the creation of a novel humanized mouse incorporating syngeneic pediatric thymus, umbilical cord blood, peripheral blood and iPSCs. This model will provide a key tool to investigate the immunogenicity of iPSC-derived tissues--a critical, yet neglected, area of research essential to the realization of iPSCs’ therapeutic potential. Relatedly, I will work to optimize the in vitro derivation of clinically-relevant quantities of re-differentiated monoclonal Tregs for pre-clinical feasibility studies.

Ryan A Denu

Ryan A Denu

Ryan A Denu earned his bachelor’s degree in Molecular Biology at UW-Madison. He is a student in the Medical Scientist Training Program who is earning the PhD in Cellular and Molecular Biology and the PhD Minor in Clinical Investigation. Ryan’s primary research project, with Mark Burkard, MD, PhD, is examining the potential oncogenic function of two mutant kinases in breast cancer. His goal is to be a physician scientist in oncology and principal investigator of a translational research laboratory.

Colin R Grove

Colin R Grove

Colin R Grove is a physical therapist and neurological clinical specialist who earned a Master of Science in Kinesiology at UW-Madison. He is pursuing dual doctoral degrees: a PhD in Clinical Investigation and a Transitional Doctor of Physical Therapy at Temple University. Colin is researching visual-vestibular stimulation in dizziness and balance rehabilitation using machine-based measures.

Kai D. Ludwig

Kai D. Ludwig

Kai D. Ludwig earned his bachelor’s degree at UW-Madison in Biochemistry. He is pursuing a PhD Minor in Clinical Investigation and the MS/PhD in Medical Physics with Professor Sean B. Fain, PhD. Kai is researching the applications of multi-nuclei Magnetic Resonance Imaging and spectroscopy to F-labeled cell trafficking for the monitoring of cancer immunotherapy and metabolism.

Andrew Voter

Andrew Voter

Andrew Voter received his bachelors degree in Chemistry and Biology at Bucknell University, Lewisburg, PA. He is currently pursuing a PhD Minor in Clinical Investigation, a PhD in the Integrated Program in Biochemistry, and an MD in the Medical Scientist Training Program. Andy is working with Biomolecular Chemistry Professor James Keck, PhD. Andy’s research is focused on small molecule screening toward DNA crosslinks to protect non-cancerous cells during therapy.

<-- back to Career Development Awards page