New ICTR RFA offers Funding and Collaboration Opportunities

Overhead view of several people working at a laptop

UW ICTR is releasing a Request for Applications (RFA) for a new competitive funding opportunity that aims to advance the commercialization of innovations to improve healthcare outcomes. The Evidence to Implementation Award is part of the ICTR commitment to supporting the integration of effective research into clinical practice to benefit health in Wisconsin and beyond.

Each award includes up to $40,000 in direct costs and substantial in-kind consultation and resources, through investigator collaboration with the new ICTR Dissemination & Implementation (D&I) Launchpad Program, for up to 18 months.

Melody Bockenfeld, ICTR D&I Launchpad Program Manager, comments:Melody Bockenfeld, MPH, BSN

We are excited to roll out this new award and look forward to forging strong partnerships with investigators to bring successful and effective health solutions to the public. This will also be the first opportunity for investigators to take advantage of the new suite of services we have developed under the D&I Launchpad Program.

This award is for researchers at UW-Madison or Marshfield Clinic Research Institute who are interested in seeing their innovations successfully implemented in healthcare settings where they will have direct, positive impacts on communities. The award is unique due to the partnership with the D&I Launchpad team, which will work in collaboration with the awardee, offering substantial in-kind support to the project.

Available services from the Launchpad team include business consultation, translation and packaging services, communication strategies, evaluation services, and implementation science guidance.

Chris Sorkness, ICTR Senior Associate Executive Director, notes:

This RFA is a big step forward in the long-term ICTR goal of offering implementation support for high-demand research inside and outside of Wisconsin’s borders. Through our unique D&I Launchpad Program, researchers will receive the comprehensive support and resources needed to see their healthcare advances make a successful, sustained leap from research to practice.

Proposed research for this RFA must include a successful intervention, care model, device, or other innovation that meets a specific demand and has potential for significant impact on healthcare or the community. Researchers must also be committed to disseminating and implementing their work broadly in practice and be open to publicly marketing their implementation materials.

The RFA is available online. A pre-proposal is due February 5, 2018. Projects chosen to proceed to the second round selection process will meet with the Launchpad team in early Spring 2018. Awards will be announced in May 2018.

Applicants are encouraged to contact Melody Bockenfeld with any questions or requests for more information.

Evidence to Implementation Award Program

Status: Active/RFA Open

This is award is intended for investigators who have developed a successful intervention that meets a specific demand in healthcare or the community and has the potential for significant impact. Investigators must be committed to disseminating and implementing their work broadly in practice and to having their implementation materials disseminated and marketed publicly. Note: For this award, investigators will work closely with the Dissemination & Implementation (D&I) Launchpad Team.

 2018-2021 Awards

Back to Main Funding Opportunities Page

Wisconsin researchers awarded $5.3 million for NIH precision medicine research

All of Us Research Program gathering biomedical data from one million people to advance medical treatments and prevention

A collaboration of three Wisconsin regional healthcare systems has been awarded $5.3 million to implement the NIH All of Us research program in Wisconsin with the goal of improving health in communities statewide.

Working with BloodCenter of Wisconsin and regional Federally Qualified Health Centers (FQHCs), Marshfield Clinic Research Institute (MCRI), UW-Madison School of Medicine and Public Health (UW SMPH), and Medical College of Wisconsin (MCW) will form a virtual statewide network to promote engagement and recruitment of Wisconsin research participants. The nationwide goal of the program is to gather health data from more than 1 million people living in the U.S. to advance precision medicine research. Dorothy Edwards, UW-Madison Collaborative Center for Health Equity (CCHE) director, comments,

Dorothy Edwards

Diseases are unique to the individual, so our aim in Wisconsin is to enroll participants who reflect the diversity of our country, providing insight to differences based on age, gender, ethnicity, and socioeconomics. The All of Us research program is an exciting opportunity for participants to play an active role in modern medicine for the benefit of their communities.

Precision medicine, also known as personalized medicine, approaches disease treatment and prevention with consideration for an individual’s biological makeup, environment, and lifestyle to help improve the treatment of diseases, such as cancer.

Murray Brilliant, director of the MCRI Center for Human Genetics, led the formation of the All of Us-Wisconsin team. Brilliant took advantage of ongoing partnerships between MCRI, UW SMPH, and MCW represented by their common membership in the NIH Clinical and Translational Science Awards (CTSA) program and the Wisconsin Genome Initiative. He says,

Murray Brilliant
Murray Brilliant

Our organizations have a long history of research collaboration and robust community engagement, and we’re proud to be involved in a program focused on a future where better prevention, detection, and treatment are possible through research.

Brilliant recruited local leaders at the UW Institute for Clinical and Translational Research (ICTR). These principal investigators for the SMPH site include Edwards and Marc Drezner, ICTR Executive Director. In addition, Umberto Tachinardi, SMPH Associate Dean of Medical Informatics and ICTR Director of Biomedical Informatics, was tapped to play a key role related to the transfer of EHR to a central All of Us repository.

This dynamic All of Us-Wisconsin team harnesses the strengths of UW including the biomedical informatics initiatives championed by UW ICTR and SMPH that have bolstered ties with UW Health and its data warehouse of patient electronic health records. Likewise, CCHE brings an array of successful programming in community engagement with members of underrepresented populations through a broad range of academic and community partners statewide. Drezner notes,

Marc Drezner

All of Us Wisconsin aims to build upon UW researchers’ innovative work in precision medicine to treat cancer to expand the approach to other diseases. We plan to leverage our existing partnerships with Marshfield Clinic, UW Health, and the UW Department of Obstetrics and Gynecology, utilizing sound research and community engagement practices, to help lay a comprehensive foundation for precision medicine.

To learn more about the All of Us research program

To read the complete project abstract

To read the official press release

2018 RFAs Announced for Pilot Awards Program

The Pilot Awards Program RFAs for projects beginning in July 1, 2018 were released November 1, 2017. This release date is one month earlier than in recent years and has been adjusted to better fit the typical schedules of both applicants and reviewers.

Peggy Hatfield, ICTR Program Manager for Translational Basic and Clinical Research Pilot Awards, comments,

Peggy Hatfield

We found that our schedule needed to be revised to accommodate both the time off that many applicants take during the winter academic break and also to give us additional time to find non-conflicted expert reviewers. Given the collaborative nature of research on the UW campus, it has been taking more time to recruit appropriate faculty for peer review of pilot award applications.

Another new feature this year is the incorporation of the NIH revised instructions for reviewing clinical trials into the pilot award review criteria. These criteria will be mandatory for applicants to NIH funding opportunities starting Jan 25, 2018. The ICTR award programs will likewise instruct local reviewers to use these additional considerations as part of their review.

RFAs released Nov 1 include Translational Basic and Clinical Research, Clinical and Community Outcomes Research (CCOR), Dissemination and Implementation (D&I) Research, and Stakeholder and Patient Engaged Research (SPER). These awards span the full spectrum of clinical and translational research. More information and complete application instructions are found on the Funding Opportunities page.

UW ICTR Receives 3rd Consecutive CTSA Grant from NIH

The leadership and staff of the University of Wisconsin Institute for Clinical and Translational Research (UW ICTR) are delighted to announce the receipt of a five-year renewal of their Clinical and Translational Science Award (CTSA) from NIH. This award of $39,876,488, from the National Center for Advancing Translational Sciences (NCATS), represents the ongoing excellence of the training programs and infrastructure support initiatives that ICTR underwrites to advance clinical and translational science at UW-Madison, Marshfield Clinic, and statewide.

UW ICTR is a partnership of four health sciences schools (Medicine and Public Health, Nursing, Pharmacy, and Veterinary Medicine) and a college (Engineering) in Madison and the Marshfield Clinic in Marshfield, WI, one of the largest private, multispecialty group practices in the United States. The institute was founded in 2007 and this award initiates the third funding cycle. In addition to ICTR, the CTSA consortium encompasses 64 (57 of which are currently funded) sites across the United States.

Marc Drezner, SMPH Senior Associate Dean for Clinical and Translational Research and Executive Director of ICTR comments,

Marc Drezner

As many people say, ‘it takes a village.’ Our success in receiving this renewal is reflective of our superb faculty and staff, as well as the institutional support we receive from many sources. ICTR succeeds because we have one of the most intensely dedicated local environments in the national CTSA consortium.

At our recent external advisory committee meeting, our reviewers applauded investments made by campus partners and leadership. Thank you!

The mission of ICTR is to support the transformation of research into a translational continuum from investigation through discovery and into community practice, thereby linking basic research to practical improvements in human health. Indeed, Robert N. Golden, Dean of the School of Medicine and Public Health and Vice-Chancellor for Medical Affairs, notes,

We are so grateful for the outstanding leadership of this wonderful institute, and the outstanding partnerships that it has created, all aimed at advancing the health of the people of Wisconsin.

Rob Lemanske, ICTR Deputy Executive Director, explains,

Rob Lemanske

ICTR uses a three-fold approach to achieve our mission. First, we provide career training for investigators and trainees at all levels to promote the development of the future workforce in clinical and translational research. Second, our very successful pilot awards program, now in its eleventh year, provides seed money and research mentoring for research areas spanning the translational spectrum. Finally, ICTR also supports an extensive array of shared services and infrastructure necessary for the conduct of translational research. These range from resources for clinical research, consultations in biostatistics and bioinformatics, to tools and partners for stakeholder-engaged research and dissemination & implementation research.

We’re also excited about the innovations we have planned for the coming years, which our grant renewal will make possible. These fronts include refining our offerings for strategic recruitment of research participants, expanding investigator training in engaging special populations in research, and supporting cutting-edge bioinformatics research for predictive medical analytics.

For more information about ICTR visit ictr.wisc.edu online or email join-ictr_news@lists.wisc.edu to be added to our mailing list for eNewsletters and major announcements.