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Targeting Estrogen Receptors and Cofactors for Precision Medicine in Breast Cancer
April 27, 2022 @ 12:00 pm - 1:00 pm
Marshfield Monthly Scientific Seminar Series
- April Topic: Targeting Estrogen Receptors and Cofactors for Precision Medicine in Breast Cancer
- When: Wednesday, April 27, 2022, 12:00 pm – 1:00 pm
- Presenter: Wei Xu, PhD, Associate Director, McArdle Laboratory for Cancer Research
- How to join meeting: Virtual meeting WebEx Link
Each month Marshfield Clinic Research Institute (MCRI) brings scientific leaders in health research to present the highlights of important health research from around the world.
To view previous topics, see the MCRI Scientific Seminar Webpage.
Hosted by: Zhi Wen, PhD
Bio: Dr. Wei Xu received B.S. in Chemistry from Beijing University and PhD from Department of Biochemistry, Univ. of Iowa in 1999. After postdoctoral training with Dr. Ronald Evans in the Salk Institute for Biological Science, she started her lab as a tenure-tracked assistant professor at Univ. of Wisconsin-Madison in 2005. She was promoted from Assistant Professor to Full Professor in 9 years. Dr. Xu is now Marian A. Messerschmidt Professor in Cancer Research and Vice Chair for Department of Oncology. Dr. Xu has received numerous awards including Department of Defense Era of Hope Scholar Award, Society of Toxicology Achievement Award, AACR-Bayer Innovation and Discovery Grant Awardee, among others. The major focus of Xu lab is on a protein arginine (R) methyltransferase CARM1/PRMT4, a nuclear hormone receptor co-activator. Using genetically engineered CARM1 knockout cell lines, Dr. Xu has identified a number of non-histone substrates for CARM1 and elucidated the function of protein arginine methylation in cancer initiation, progression and metastasis.