For questions about project management services associated with the ICTR Office of Therapeutics Discovery & Development (OTDD), please contact Rob Hagan, Drug Discovery & Development Project Manager.
This office works to enhance the availability of resources along the therapeutics discovery and development critical path, help investigators develop a network of internal and external innovation partners, and identify and support 3-5 projects per year with specialized assistance in project management.
Assistance with project management emphasizes:
- Evaluating the feasibility and likelihood for success in early stages, i.e., fail early.
- Providing resources for projects that are too early for private investment or not fundable via traditional extramural sources, e.g., NIH, NSF, DOD.
- Increasing licensability by generating proof-of-concept data, i.e. moving projects along the development path to create a robust data portfolio
RECOMMENDED RESOURCES AT NIH/NCATS FOR DRUG DISCOVERY AND DEVELOPMENT
(Courtesy of Dr. Anton Simeonov, Director of Preclinical Innovation at NCATS)
Early Translation Branch (ETB) – Successor to the NIH Chemical Genomics Center originally created in 2004 to develop small molecule probes to study under explored areas of human disease biology.
3-D Tissue Bioprinting Program – Works to create and validate tissues and tissue equivalents as models for human physiology for both toxicity evaluations on healthy tissues and therapeutic efficacy investigations using diseased tissues.
Antiviral Program for Pandemics (APP) – A recently launched initiative to prospectively develop antivirals for future pandemics.
Therapeutics for Rare and Neglected Diseases (TRND) – A late-stage drug development program focused on rare genetic diseases and neglected tropical infections.