For questions about project management services associated with the ICTR Office of Therapeutics Discovery & Development (OTDD), please contact Rob Hagan, Drug Discovery & Development Project Manager.
This office works to enhance the availability of resources along the therapeutics discovery and development critical path, help investigators develop a network of internal and external innovation partners, and identify and support 3-5 projects per year with specialized assistance in project management.
Assistance with project management emphasizes:
- Evaluating the feasibility and likelihood for success in early stages, i.e., fail early.
- Providing resources for projects that are too early for private investment or not fundable via traditional extramural sources, e.g., NIH, NSF, DOD.
- Increasing licensability by generating proof-of-concept data, i.e. moving projects along the development path to create a robust data portfolio
RECOMMENDED RESOURCES AT NIH/NCATS FOR DRUG DISCOVERY AND DEVELOPMENT
(Courtesy of Dr. Anton Simeonov, Director of Preclinical Innovation at NCATS)
Early Translation Branch (ETB) – Successor to the NIH Chemical Genomics Center originally created in 2004 to develop small molecule probes to study under explored areas of human disease biology.
https://ncats.nih.gov/etb
https://ncats.nih.gov/etb/work
3-D Tissue Bioprinting Program – Works to create and validate tissues and tissue equivalents as models for human physiology for both toxicity evaluations on healthy tissues and therapeutic efficacy investigations using diseased tissues.
https://ncats.nih.gov/bioprinting
https://ncats.nih.gov/bioprinting/about/operations
Antiviral Program for Pandemics (APP) – A recently launched initiative to prospectively develop antivirals for future pandemics.
https://ncats.nih.gov/antivirals
Therapeutics for Rare and Neglected Diseases (TRND) – A late-stage drug development program focused on rare genetic diseases and neglected tropical infections.
https://ncats.nih.gov/trnd
https://ncats.nih.gov/trnd/work/solicitation