Position title: Current TL1 Trainee
Mason Shipley is pursuing a PhD in Cellular and Molecular Pathology.
Using the Molecular Mechanisms of HSV Reactivation to Design Novel Treatments to Prevent Human Ocular Disease
We hypothesize that CTRL2 loops the HSV-1 genome into a latent structure that links the LAT enhancer to expression of both the IE and anterograde transport genes to ensure that reactivation events that are initiated (by turning on IE gene expression) can result in the successful anterograde transport of assembled infectious virions (by turning on the expression of the anterograde cluster).
Mentor: Donna Neumann, PhD, McPherson Eye Research Institute